T1 - Serum vitamin K1 associated to micro- and/or macroangiopathy in individuals with and without diabetes. T2 - Serum vitamin K1 and micro- and macroangiopathy. AU - Bøgh Andersen, Ida. AU - Brasen, Claus Lohman. AU - Nasimi, Hashmatullah . AU - Stougaard, Maria. AU - Bliddal, Mette. AU - Green, Anders. AU - Schmedes, Anne. AU - Brandslund, Ivan
RESEARCH DESIGN AND METHODS Patients with proliferative diabetic retinopathy and a carotid intima-media thickness (IMT) level ≤1.0 mm were classified as the microangiopathy group (MIG); those with an IMT level >1.1 mm and without retinopathy or with background retinopathy were assigned to the macroangiopathy group (MAG).
CONCLUSIONS: In a representative population of type 2 diabetes, PSN is related to microvascular and macrovascular pathology. PSN is possibly affected by the IGF axis. PMCID: PMC2628701 PMID: 19033412 [Indexed for MEDLINE] Publication Types: Research Support, Non-U.S. Gov't; MeSH terms. Adult; Aged; Diabetes Mellitus, Type 2/physiopathology* Peripheral sensory neuropathy (PSN) is a well-known complication of diabetes attributed to chronic hyperglycemia (1,2). However, the risk of PSN is also increased by advancing age and affected by height and possibly by sex (3) and poorly defined factors, such as processes coupled to regulation of IGF-1 (4,5). Microangiopathy of diabetic renal disease occurs in two thirds of diabetic patients 20 years after the onset of the disease; microangiopathy generally causes proteinuria.1 Within 5 years of the onset of proteinuria, uremia may ensue.
RESEARCH DESIGN AND METHODS Patients with proliferative diabetic retinopathy and a carotid intima-media thickness (IMT) level ≤1.0 mm were CONCLUSIONS—In a representative population of type 2 diabetes, PSN is related to microvascular and macrovascular pathology. PSN is possibly affected by the IGF axis. Peripheral sensory neuropathy (PSN) is a well-known complication of diabetes attributed to chronic hyperglycemia (1,2). Molecular mechanisms of macroangiopathy in diabetes 3.1. The AGEs/RAGEs system and the new molecular mediator, CTRP1: linking inflammation and altered metabolic processes 3.2. The TLR-2 and -4 signaling pathways. Inflammation is a key event characterizing and promoting the early steps of 3.3.
the “Micro- & macroangiopathy” group. They could for instances have one microangiopathic and one macroan-giopathic diagnosis or a single operational code that qual-ified as both microangiopathic and macroangiopathic disease, that is, for a type of amputation. Individuals in the “Unspecified group” had one or more diabetes-
Serum vitamin K1 associated to micro- and/or macroangiopathy in individuals with and without diabetes: Serum vitamin K1 and micro- and macroangiopathy. Ida Bøgh Andersen, Claus Lohman Brasen, Hashmatullah Nasimi, Maria Stougaard, Mette Bliddal, Anders Green, Anne Schmedes, Ivan Brandslund, Jonna Skov Madsen.
Diabetic micro- and macroangiopathy are characterized by lesions of the small and large blood vessels of the legs, heart and brain, and show severe form of diabetes of any type. Clinically, these complications, accordingly, appear in the form of diabetic foot syndrome, and occlusive vascular lesions of the lower limbs, cardiomyopathy and coronary
Ang macroangiopathy ng diabetes ay isang kumplikadong patolohiya na bubuo bilang isang resulta ng hindi sapat na paggamot at hindi pagsunod sa mga reseta ng doktor para sa diyabetis. Mapanganib ang sakit at nangangailangan ng sapat na therapy. microangiopathy: [ mi″kro-an″je-op´ah-the ] a disorder involving the small blood vessels. adj., adj microangiopath´ic. thrombotic microangiopathy formation of thrombi in the arterioles and capillaries; proposed name for a syndrome that would include both thrombotic thrombocytopenic purpura and hemolytic uremic syndrome .
Comparison Between NIDDM Patients with Microvascular Angina and Those with CAD. CORONARY MIcRo@
opment of microangiopathy is apparent. The compa- rison of Type I diabetic patients who develop micro- angiopathy very early in the course of diabetes with. Early diagnosis of diabetes mellitus complications reduces their progression of diabetes would allow for detection of macroangiopathy and microangiopathy in detección de complicaciones crónicas de la diabetes permite detectar micr
These complications occur in the majority of individuals with both type 1 and type 2 diabetes. Among the most prevalent microvascular complications are kidney
glycemic control and duration of diabetes, con- ventional markers of macro- and micro-vascular disease are strongly associated with DPN4.
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However, this study was considered sufficient to demonstrate the high incidence of decreased eGFR (<60 mL/min/1.73 m 2) with normoalbuminuria in patients with type 2 diabetes mellitus and a high frequency of diabetic micro- and macroangiopathies in this group compared with eGFR ≥ 60 mL/min/1.73 m 2 in a large number of subjects. Plasma level of retinol and of alpha-tocopherol in non-insulin dependent diabetes mellitus: its relation to micro- or macroangiopathy By G. Seghieri, L. Martinoli, M. Di Felice, R. Anichini, F. Bennardini, R. Gori, G. C. Bartolomei and F. Franconi Possible causes include defects in immunity, an increased adherence of microorganisms to diabetic cells, the presence of micro- and macroangiopathy or neuropathy, and the high number of medical interventions in this group of patients. The immune system can be divided into the innate and adaptive-humoral or cellular immune systems. Abstract.
CONCLUSIONS —In a representative population of type 2 diabetes, PSN is related to microvascular and macrovascular pathology.
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Therefore, it is important to carry out intensive examinations for the detection of diabetic micro-and macroangiopathies, in addition to the evaluation of treating some of the easily correctable causes of anemia, such as nutritional deficiency, medications, occult bleeding, inflammatory diseases, hemolysis, thyroid and other disorders when mild anemia is found in patients with type 2 diabetes
Further, data also showed that polymorphism of the TNF gene increases the risk of diabetic micro- The prevailing opinion appears to be that diabetes accelerates the mechanism that leads to development of classical atherosclerosis. However, as an alternative, we have amassed data that point to the presence of a diabetic macroangiopathy. This phenomenon comprises a constellation of nonatherosclerotic large vessel abnormalities. Diabetic macroangiopathy – a specific form of accelerated atherosclerosis – is characterized by intra-plaque new vessel formation due to excessive/abnormal neovasculogenesis and angiogenesis, increased vascular permeability of the capillary vessels, and tissue edema, resulting in frequent atherosclerotic plaque hemorrhage and plaque rupture. On the other hand, diabetes is known to induce micro-and macroangiopathy, with microangiopathy causing nephropathy, retinopathy or neuropathy, and macroangiopathy contributing to the development of Abstract. OBJECTIVE Although persistent hyperglycemia contributes greatly to the progression of diabetic micro- and macroangiopathy, microangiopathy progresses more rapidly than macroangiopathy in some type 2 diabetic patients, with the opposite being true in others. This study was conducted to identify factors responsible for such dissociation.
INTRODUCTION: There is evidence of increased macro- and micro-vascular risk in diabetic patients. The objective of this study was to determine the level of control in patients in different population groups with type 2 diabetes. MATERIAL AND METHODS: Descriptive cross-sectional study.
Peripheral sensory neuropathy associates with micro- or macroangiopathy : Results from a population based study of patients with type 2 diabetes in Sweden Cheiroarthropathy in relation to micro and macroangiopathy in type- I diabetes mellitus.
Gov't; MeSH terms. Adult; Aged; Diabetes Mellitus, Type 2/physiopathology* Peripheral sensory neuropathy (PSN) is a well-known complication of diabetes attributed to chronic hyperglycemia (1,2). However, the risk of PSN is also increased by advancing age and affected by height and possibly by sex (3) and poorly defined factors, such as processes coupled to regulation of IGF-1 (4,5). Microangiopathy of diabetic renal disease occurs in two thirds of diabetic patients 20 years after the onset of the disease; microangiopathy generally causes proteinuria.1 Within 5 years of the onset of proteinuria, uremia may ensue.